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PRP Injections for Neuropathy

Perineural PRP for painful diabetic neuropathy: what the randomised trial found, who may benefit and what to expect.

Medically reviewed by Dr James Bristol, MD, PhD · Updated 2026-11-15

PRP (platelet-rich plasma) injected around nerves is being studied for painful diabetic neuropathy. A randomised trial (Hassanien, 2020) found patients who received perineural PRP reported less pain and better nerve test results than those on medicines alone. It is one small trial, so evidence is limited.

Who it may suit

Burning, numb or tingling feet for months? Get the free guide and a doctor review of your scan.

What to expect

PRP is sometimes combined with stem cell approaches. A doctor decides what could fit after reviewing your history.

PRP and stem cells together

PRP delivers growth factors from your own blood; stem cells release a wider range of repair signals. Many treatment plans combine both to support nerves and their blood supply. A doctor decides the right combination after reviewing your case.

Who it may suit

Burning, numb or tingling feet for months? Get the free guide and a doctor review of your scan.

Recovery

Mild soreness at injection sites for a day or two. Most people walk normally the same day and continue usual activity. Changes build over weeks.

Common questions

Is PRP safe? It uses your own blood, so allergic reactions are very unlikely; injection-site soreness is the most common side effect.

How many sessions? Plans vary; a doctor will tell you after reviewing your case.

Free guide · Step 1 of 2

Free assessment: could stem cells help your nerves?

Our doctor reviews your case free and tells you whether stem cell treatment could help your nerves. Plus the 7-step neuropathy relief guide, on WhatsApp.

Step 2 of 2

Last step: do you have nerve test results or a medical report?

If yes, a doctor reviews it for free and tells you whether regenerative or other non-surgical options could suit you.

WhatsApp opens with your message ready. Tap send, then tap the paperclip to attach your report or photos.