PRP (platelet-rich plasma) injected around nerves is being studied for painful diabetic neuropathy. A randomised trial (Hassanien, 2020) found patients who received perineural PRP reported less pain and better nerve test results than those on medicines alone. It is one small trial, so evidence is limited.
Who it may suit
- Painful diabetic neuropathy not controlled by medicines
- People looking for non-drug options
Burning, numb or tingling feet for months? Get the free guide and a doctor review of your scan.
What to expect
- Blood drawn and spun to concentrate platelets
- Ultrasound-guided injections around nerves in the leg
- Effects, if any, build over weeks
PRP is sometimes combined with stem cell approaches. A doctor decides what could fit after reviewing your history.
PRP and stem cells together
PRP delivers growth factors from your own blood; stem cells release a wider range of repair signals. Many treatment plans combine both to support nerves and their blood supply. A doctor decides the right combination after reviewing your case.
Who it may suit
- Painful diabetic neuropathy despite medicines
- People who prefer a treatment using their own blood
- People with side effects from nerve-pain tablets
Burning, numb or tingling feet for months? Get the free guide and a doctor review of your scan.
Recovery
Mild soreness at injection sites for a day or two. Most people walk normally the same day and continue usual activity. Changes build over weeks.
Common questions
Is PRP safe? It uses your own blood, so allergic reactions are very unlikely; injection-site soreness is the most common side effect.
How many sessions? Plans vary; a doctor will tell you after reviewing your case.



