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The cause of neuropathy shapes the treatment. Diabetes is the most common cause worldwide; chemotherapy and HIV are major causes in people treated for those conditions.
Type Key facts Diabetic neuropathy Starts in the toes, often both feet Chemotherapy-induced Linked to platinum drugs, taxanes, vinca alkaloids, bortezomib HIV-related Distal sensory polyneuropathy, feet first B12 deficiency Common with long-term metformin or poor absorption; treatable Alcohol-related Can improve after stopping alcohol Idiopathic No cause found in a share of people
Symptoms: neuropathy in the feet , burning feet , numbness and tingling .
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Evidence drawn from
NICE guidelines Diabetes Care Journal of Clinical Oncology Neurology Pain Medicine Nature Medicine Stem Cell Research & Therapy Stem Cells Transl Med
Burning Feet Why feet burn at night: small-fibre neuropathy causes such as diabetes and B12 deficiency, quick relief and… Neuropathy from Chemotherapy Chemotherapy-induced peripheral neuropathy: which drugs cause it, what helps, duloxetine, exercise and… Diabetic Neuropathy Diabetic neuropathy symptoms and treatment: blood sugar, B12, first-line medicines, foot care and new options… HIV-Related Neuropathy HIV-associated sensory neuropathy: causes, treatment options including capsaicin patch, foot care and… Neuropathy in the Feet Peripheral neuropathy in the feet: burning, tingling and numbness, common causes, foot care and treatment… Numbness and Tingling Causes of numbness and tingling in the hands and feet, warning signs and what to do… 
